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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
WP1066 Influence on tumor growth Tumor volume 40.00 mg/kg Caki-1 (xenograft) Mus musculus athymic male nude
WP1066 Influence on tumor growth Immunohistochemistry 40.00 mg/kg Caki-1 (xenograft) Mus musculus athymic male nude p-STAT3
WP1066 Influence on tumor growth Immunohistochemistry 40.00 mg/kg Caki-1 (xenograft) Mus musculus athymic male nude STAT3
WP1066 Influence on tumor growth Immunohistochemistry 40.00 mg/kg Caki-1 (xenograft) Mus musculus athymic male nude
WP1066 Influence on tumor growth Tumor volume 40.00 mg/kg B16EGFRvIII (xenograft) Mus musculus C57BL/6J
WP1066 Influence on tumor growth Percent survival 10.00 mg/kg B16EGFRvIII (xenograft) Mus musculus C57BL/6J
WP1066 Influence on tumor growth Percent survival 20.00 mg/kg B16EGFRvIII (xenograft) Mus musculus C57BL/6J
WP1066 Influence on tumor growth Percent survival 40.00 mg/kg B16 (xenograft) Mus musculus C57BL/6J
WP1066 Influence on cell tumor growth Tumor size 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice
WP1066 Influence on cell proliferation on tumor tissue Immunostaining 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice
WP1066 Influence on cell apoptosis on tumor tissue Immunostaining 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice STAT3
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice p-STAT3
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice
WP1066 Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg gp130757FF tumor tissue Mus musculus gp130 757FF mice
WP1066 Influence on pro-inflammatory gene expression Real-time qPCR 10.00 mg/kg antral stomach tissue Mus musculus gp130 757FF mice
WP1066 Influence on pro-inflammatory gene expression Real-time qPCR 10.00 mg/kg antral stomach tissue Mus musculus gp130 757FF mice
WP1066 Influence on pro-inflammatory gene expression Real-time qPCR 10.00 mg/kg antral stomach tissue Mus musculus gp130 757FF mice
WP1066 Influence on pro-inflammatory gene expression Real-time qPCR 10.00 mg/kg antral stomach tissue Mus musculus gp130 757FF mice
WP1066 Influence on pro-inflammatory gene expression Real-time qPCR 10.00 mg/kg antral stomach tissue Mus musculus gp130 757FF mice